Pakistan says it cannot find mpox patient as tighter screening introduced at airports

Pakistan says it is introducing new screening at airports after confirming at least one case of mpox infection, days after the World Health Organisation declared a global emergency over the virus.

Health officials are concerned about a new deadlier strain of the virus, formerly known as monkeypox, that has spread through several African countries..

The single case reported in Pakistan involves a patient who had recently returned from a Gulf country. Pakistan’s health ministry said it was yet to determine the strain of the virus involved.

Mpox belongs to the smallpox family of viruses but causes milder symptoms including fever, chills and body aches, with more serious cases likely to develop characteristic lesions on the face, hands, chest and genitals.

Earlier this week, the WHO warned of the “very worrying” emergence and spread of a new variant of mpox associated with a “more severe disease and higher mortality rates” than the strain behind the global mpox outbreak in 2022.

Over 17,000 mpox cases have been confirmed in Africa with more than 500 deaths this year alone, mainly among children in Congo since the outbreak began at the start of 2023.

Pakistan’s health department confirmed that one case of mpox was detected in the country’s northern Khyber Pakhtunkwa province, withdrawing a previous statement that three cases of the viral infection were detected in the region this week on arrival from the UAE.

The health ministry said it is yet to confirm if the patient is infected with the new variant known as clade 1b, with the sequencing of a sample from the Khyber Pakhtunkwa patient underway.

“Once that’s done, we will be able to say what strain this is,” the health ministry said, adding that the “screening system at airports and entry points is being further strengthened”.

The ministry flagged concerns that the location of the confirmed mpox patient in Pakistan is currently unknown, as he is suspected to have gone to another district after providing his samples for tests.

“When we visited his home in Mardan, it was locked from outside and his neighbours told us that the family has left for Dir,” the district health office (DHO) said.

“We approached our fellow colleagues of the health department in Dir district, but they couldn’t trace him even in Dir,” the DHO said.

The health ministry said it was carrying out contact tracing of the patient.

The new strain known as clade 1b emerged in a Congolese mining town last year and is spreading to other countries in Africa as well as one case confirmed in Sweden on Thursday.

This strain is said to cause milder symptoms with lesions on the genitals, making it harder to spot and more likely for people to sicken others without knowing they’re infected.

TClade 1b “is concerning for two main reasons,” according to pox researcher Jonas Albarnaz from the Pirbright Institute.

“Frst, this is the first clade 1 mpox virus case outside Africa. This indicates that the extent of the international spread of clade 1 outbreak in DRC might be larger than we knew yesterday,” Dr Albarnaz said.

“And second, clade 1 mpox virus is associated with a more severe disease and higher mortality rates than the clade 2 virus responsible for the international mpox outbreak in 2022,” he said.