The Red Devils entered the international break on the back of two consecutive defeats, the last of which came against bitter rivals Liverpool.
It piled more pressure on Erik ten Hag, who has rarely wholly convinced in the United dugout since winning the Carabao Cup during his first season in charge.
Anything other than three points on the south coast would be a major disappointment. Saints are yet to win this season, making Ten Hag’s side huge favourites.
Here’s everything you need to know about where to watch the game.
How to watch Southampton vs Manchester United
TV channel: The game will be broadcast on TNT Sports 1 and TNT Sports Ultimate. Coverage starts at 11am BST ahead of a 12.30pm kick-off.
Live stream: Subscribers will be able to watch on a live stream via the Discovery+ app.
LIVE coverage: Follow all the action with Standard Sport’s dedicated match blog!
