City currently sit top of the table following a brilliant start to the season, having won all four of their games thus far.
Defeat to Arsenal, who took four points off Pep Guardiola’s side last year, would see them cede top spot – with the Gunners reaching the summit.
Here’s everything you need to know about the game.
Date, kick-off time and venue
Man City vs Arsenal is scheduled for a 4.30pm BST kick-off time on Sunday 22 September, 2024.
The Etihad Stadium in Manchester will host.
Where to watch Man City vs Arsenal
TV channel: The game will be broadcast on Sky Sports Main Event, Sky Sports Premier League and Sky Sports Ultra HDR.
Live stream: Subscribers will be able to watch via the Sky Go app.
LIVE coverage: Follow all the action with Standard Sport’s dedicated match blog!
Man City vs Arsenal team news
Oscar Bobb and Nathan Ake, meanwhile, are definitely out for the champions.
Big blow: Martin Odegaard is facing an extended period out of action
Action Images via Reuters
Still out for the Gunners are Takehiro Tomiyasu, Kieran Tierney, Oleksandr Zinchenko and Mikel Merino.
Man City vs Arsenal prediction
Neither team will want to give much away this early into the season.
Head to head (h2h) history and results
Man City vs Arsenal latest odds
Odds via Betfair and subject to change.